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Latent Space: The AI Engineer Podcast artwork

Latent Space: The AI Engineer Podcast

219 episodes

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🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery artwork

🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

Latent Space: The AI Engineer Podcast

1:35:19Aug 11, 2026
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten artwork

The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Latent Space: The AI Engineer Podcast

1:41:29Aug 3, 2026
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI artwork

Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

Latent Space: The AI Engineer Podcast

1:09:28Jul 28, 2026
Inside the Model Factory — Eiso Kant, Poolside AI artwork

Inside the Model Factory — Eiso Kant, Poolside AI

Latent Space: The AI Engineer Podcast

1:54:33Jul 23, 2026
🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist) artwork

🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

Latent Space: The AI Engineer Podcast

1:29:47Jul 21, 2026
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences artwork

🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

Latent Space: The AI Engineer Podcast

1:41:04Jul 16, 2026
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO artwork

Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

Latent Space: The AI Engineer Podcast

57:55Jul 8, 2026
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI artwork

🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

Latent Space: The AI Engineer Podcast

1:48:39Jul 1, 2026
Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks artwork

Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

Latent Space: The AI Engineer Podcast

1:08:52Jun 24, 2026
Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan artwork

Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

Latent Space: The AI Engineer Podcast

1:06:23Jun 22, 2026
The Professor of Outputmaxxing — Anjney Midha, AMP artwork

The Professor of Outputmaxxing — Anjney Midha, AMP

Latent Space: The AI Engineer Podcast

59:25Jun 18, 2026
🔬 The Self-Driving Lab — Joseph Krause, Radical AI  artwork

🔬 The Self-Driving Lab — Joseph Krause, Radical AI

Latent Space: The AI Engineer Podcast

1:16:50Jun 17, 2026
Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs artwork

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

Latent Space: The AI Engineer Podcast

1:15:39Jun 4, 2026
🔬Scaling Past Informal AI - Carina Hong, Axiom Math artwork

🔬Scaling Past Informal AI - Carina Hong, Axiom Math

Latent Space: The AI Engineer Podcast

1:33:04Jun 3, 2026
⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build artwork

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

Latent Space: The AI Engineer Podcast

38:58Jun 3, 2026
GitHub's plan for Agents — Kyle Daigle, GitHub artwork

GitHub's plan for Agents — Kyle Daigle, GitHub

Latent Space: The AI Engineer Podcast

1:23:27Jun 2, 2026
Why Video Agent models are next — Ethan He, xAI Grok Imagine artwork

Why Video Agent models are next — Ethan He, xAI Grok Imagine

Latent Space: The AI Engineer Podcast

1:43:26Jun 1, 2026
The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray artwork

The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray

Latent Space: The AI Engineer Podcast

1:08:02May 28, 2026
🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub artwork

🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

Latent Space: The AI Engineer Podcast

1:10:12May 27, 2026
Giving Agents Computers — Ivan Burazin, Daytona artwork

Giving Agents Computers — Ivan Burazin, Daytona

Latent Space: The AI Engineer Podcast

1:10:27May 21, 2026
Railway: The Agent-Native Cloud — Jake Cooper artwork

Railway: The Agent-Native Cloud — Jake Cooper

Latent Space: The AI Engineer Podcast

1:28:34May 20, 2026
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion artwork

The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion

Latent Space: The AI Engineer Podcast

1:59:28May 18, 2026
AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge artwork

AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

Latent Space: The AI Engineer Podcast

1:05:20May 14, 2026
🔬Doing Vibe Physics — Alex Lupsasca, OpenAI artwork

🔬Doing Vibe Physics — Alex Lupsasca, OpenAI

Latent Space: The AI Engineer Podcast

1:31:51May 5, 2026
Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition artwork

Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition

Latent Space: The AI Engineer Podcast

1:12:21Apr 27, 2026
AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026) artwork

AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)

Latent Space: The AI Engineer Podcast

54:52Apr 23, 2026
Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO artwork

Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO

Latent Space: The AI Engineer Podcast

1:12:25Apr 22, 2026
🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik artwork

🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik

Latent Space: The AI Engineer Podcast

1:25:21Apr 20, 2026
Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion artwork

Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion

Latent Space: The AI Engineer Podcast

1:17:17Apr 15, 2026
Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony artwork

Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony

Latent Space: The AI Engineer Podcast

1:12:43Apr 7, 2026
Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different" artwork

Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"

Latent Space: The AI Engineer Podcast

1:16:20Apr 3, 2026
Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun artwork

Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun

Latent Space: The AI Engineer Podcast

1:06:47Apr 2, 2026
Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample artwork

Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample

Latent Space: The AI Engineer Podcast

48:48Mar 30, 2026
🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik artwork

🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik

Latent Space: The AI Engineer Podcast

35:14Mar 24, 2026
Dreamer: the Personal Agent OS — David Singleton artwork

Dreamer: the Personal Agent OS — David Singleton

Latent Space: The AI Engineer Podcast

1:03:35Mar 20, 2026
Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop artwork

Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop

Latent Space: The AI Engineer Podcast

1:26:59Mar 17, 2026
Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer artwork

Retrieval After RAG: Hybrid Search, Agents, and Database Design — Simon Hørup Eskildsen of Turbopuffer

Latent Space: The AI Engineer Podcast

1:00:32Mar 12, 2026
NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo) artwork

NVIDIA's AI Engineers: Agent Inference at Planetary Scale and "Speed of Light" — Nader Khalil (Brev), Kyle Kranen (Dynamo)

Latent Space: The AI Engineer Podcast

1:23:37Mar 10, 2026
Cursor's Third Era: Cloud Agents artwork

Cursor's Third Era: Cloud Agents

Latent Space: The AI Engineer Podcast

1:06:39Mar 6, 2026
Every Agent Needs a Box — Aaron Levie, Box artwork

Every Agent Needs a Box — Aaron Levie, Box

Latent Space: The AI Engineer Podcast

1:16:58Mar 5, 2026
METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity artwork

METR’s Joel Becker on exponential Time Horizon Evals, Threat Models, and the Limits of AI Productivity

Latent Space: The AI Engineer Podcast

56:14Feb 27, 2026
[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka artwork

[LIVE] Anthropic Distillation & How Models Cheat (SWE-Bench Dead) | Nathan Lambert & Sebastian Raschka

Latent Space: The AI Engineer Podcast

52:17Feb 26, 2026
🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI artwork

🔬Searching the Space of All Possible Materials — Prof. Max Welling, CuspAI

Latent Space: The AI Engineer Podcast

33:56Feb 25, 2026
Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis artwork

Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis

Latent Space: The AI Engineer Podcast

2:04:13Feb 24, 2026
⚡️The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data artwork

⚡️The End of SWE-Bench Verified — Mia Glaese & Olivia Watkins, OpenAI Frontier Evals & Human Data

Latent Space: The AI Engineer Podcast

26:12Feb 23, 2026
Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z artwork

Bitter Lessons in Venture vs Growth: Anthropic vs OpenAI, Noam Shazeer, World Labs, Thinking Machines, Cursor, ASIC Economics — Martin Casado & Sarah Wang of a16z

Latent Space: The AI Engineer Podcast

55:18Feb 19, 2026
Owning the AI Pareto Frontier — Jeff Dean artwork

Owning the AI Pareto Frontier — Jeff Dean

Latent Space: The AI Engineer Podcast

1:23:31Feb 12, 2026
🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery artwork

🔬Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery

Latent Space: The AI Engineer Podcast

1:21:07Feb 12, 2026
The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI artwork

The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI

Latent Space: The AI Engineer Podcast

1:08:01Feb 6, 2026
🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White artwork

🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White

Latent Space: The AI Engineer Podcast

1:13:56Jan 28, 2026