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Latent Space: The AI Engineer Podcast artwork

Latent Space: The AI Engineer Podcast

233 episodes

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Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub artwork

Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

Latent Space: The AI Engineer Podcast

31:56Oct 10, 2026
Synthesis Superintelligence: from Semiconductors to Superconductors — Periodic Labs’ Liam Fedus and Ekin Dogus Cubuk artwork

Synthesis Superintelligence: from Semiconductors to Superconductors — Periodic Labs’ Liam Fedus and Ekin Dogus Cubuk

Latent Space: The AI Engineer Podcast

1:24:00Oct 8, 2026
Academia is for Ambition — Alex Zhang, MIT artwork

Academia is for Ambition — Alex Zhang, MIT

Latent Space: The AI Engineer Podcast

1:41:28Oct 2, 2026
Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week artwork

Why Dwarkesh is Wrong about Computer Use + How OpenAI shipped its Jev competitor in 1 Week

Latent Space: The AI Engineer Podcast

39:12Sep 30, 2026
Claude Code’s Next Era — Thariq Shihipar, Anthropic artwork

Claude Code’s Next Era — Thariq Shihipar, Anthropic

Latent Space: The AI Engineer Podcast

1:32:29Sep 29, 2026
OpenRouter: from Seed to Stripe — with OpenRouter’s Alex Atallah & AMP’s Anjney Midha artwork

OpenRouter: from Seed to Stripe — with OpenRouter’s Alex Atallah & AMP’s Anjney Midha

Latent Space: The AI Engineer Podcast

1:20:43Sep 25, 2026
Runway’s WorldPrompt and the Engineering of Real-Time Worlds artwork

Runway’s WorldPrompt and the Engineering of Real-Time Worlds

Latent Space: The AI Engineer Podcast

1:36:21Sep 25, 2026
🔬Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics) artwork

🔬Bio-security is an AI Arms Race - Eric Nguyen (CEO, Radical Numerics)

Latent Space: The AI Engineer Podcast

1:31:58Sep 23, 2026
🔬 An Oscar, Two Asteroids, and the Algorithm in Your sklearn: John Platt on AI for Science artwork

🔬 An Oscar, Two Asteroids, and the Algorithm in Your sklearn: John Platt on AI for Science

Latent Space: The AI Engineer Podcast

2:01:26Sep 22, 2026
Jev: System One models for Prod, not God — with Diogo Almeida, CEO, TypeSafe AI artwork

Jev: System One models for Prod, not God — with Diogo Almeida, CEO, TypeSafe AI

Latent Space: The AI Engineer Podcast

2:20:53Sep 21, 2026
Underwriting Superintelligence: Backing Agents you can Sue — Rune Kvist, AIUC artwork

Underwriting Superintelligence: Backing Agents you can Sue — Rune Kvist, AIUC

Latent Space: The AI Engineer Podcast

1:26:14Sep 16, 2026
Humanity’s Last Invention — Richard Socher of Recursive artwork

Humanity’s Last Invention — Richard Socher of Recursive

Latent Space: The AI Engineer Podcast

1:32:10Sep 14, 2026
🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing artwork

🔬“We have foundation models for language, not for physics” — Anima Anandkumar, Bren Professor of Computing

Latent Space: The AI Engineer Podcast

1:23:31Aug 26, 2026
Simulation: the new Scaling Law — Joon Sung Park, Simile AI artwork

Simulation: the new Scaling Law — Joon Sung Park, Simile AI

Latent Space: The AI Engineer Podcast

1:09:38Aug 21, 2026
🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery artwork

🔬The BioAI Phase Shift - Matthew McPartlon & Neil Patil, Chai Discovery

Latent Space: The AI Engineer Podcast

1:35:19Aug 11, 2026
The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten artwork

The Inference Engineering Masterclass — Philip Kiely & Ali Taha, Baseten

Latent Space: The AI Engineer Podcast

1:41:29Aug 3, 2026
Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI artwork

Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

Latent Space: The AI Engineer Podcast

1:09:28Jul 28, 2026
Inside the Model Factory — Eiso Kant, Poolside AI artwork

Inside the Model Factory — Eiso Kant, Poolside AI

Latent Space: The AI Engineer Podcast

1:54:33Jul 23, 2026
🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist) artwork

🔬Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

Latent Space: The AI Engineer Podcast

1:29:47Jul 21, 2026
🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences artwork

🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

Latent Space: The AI Engineer Podcast

1:41:04Jul 16, 2026
Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO artwork

Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

Latent Space: The AI Engineer Podcast

57:55Jul 8, 2026
🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI artwork

🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

Latent Space: The AI Engineer Podcast

1:48:39Jul 1, 2026
Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks artwork

Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

Latent Space: The AI Engineer Podcast

1:08:52Jun 24, 2026
Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan artwork

Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

Latent Space: The AI Engineer Podcast

1:06:23Jun 22, 2026
The Professor of Outputmaxxing — Anjney Midha, AMP artwork

The Professor of Outputmaxxing — Anjney Midha, AMP

Latent Space: The AI Engineer Podcast

59:25Jun 18, 2026
🔬 The Self-Driving Lab — Joseph Krause, Radical AI artwork

🔬 The Self-Driving Lab — Joseph Krause, Radical AI

Latent Space: The AI Engineer Podcast

1:16:50Jun 17, 2026
Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs artwork

Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

Latent Space: The AI Engineer Podcast

1:15:39Jun 4, 2026
🔬Scaling Past Informal AI - Carina Hong, Axiom Math artwork

🔬Scaling Past Informal AI - Carina Hong, Axiom Math

Latent Space: The AI Engineer Podcast

1:33:04Jun 3, 2026
⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build artwork

⚡️Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

Latent Space: The AI Engineer Podcast

38:58Jun 3, 2026
GitHub's plan for Agents — Kyle Daigle, GitHub artwork

GitHub's plan for Agents — Kyle Daigle, GitHub

Latent Space: The AI Engineer Podcast

1:23:27Jun 2, 2026
Why Video Agent models are next — Ethan He, xAI Grok Imagine artwork

Why Video Agent models are next — Ethan He, xAI Grok Imagine

Latent Space: The AI Engineer Podcast

1:43:26Jun 1, 2026
The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray artwork

The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray

Latent Space: The AI Engineer Podcast

1:08:02May 28, 2026
🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub artwork

🔬ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

Latent Space: The AI Engineer Podcast

1:10:12May 27, 2026
Giving Agents Computers — Ivan Burazin, Daytona artwork

Giving Agents Computers — Ivan Burazin, Daytona

Latent Space: The AI Engineer Podcast

1:10:27May 21, 2026
Railway: The Agent-Native Cloud — Jake Cooper artwork

Railway: The Agent-Native Cloud — Jake Cooper

Latent Space: The AI Engineer Podcast

1:28:34May 20, 2026
The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion artwork

The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion

Latent Space: The AI Engineer Podcast

1:59:28May 18, 2026
AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge artwork

AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

Latent Space: The AI Engineer Podcast

1:05:20May 14, 2026
🔬Doing Vibe Physics — Alex Lupsasca, OpenAI artwork

🔬Doing Vibe Physics — Alex Lupsasca, OpenAI

Latent Space: The AI Engineer Podcast

1:31:51May 5, 2026
Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition artwork

Physical AI that Moves the World — Qasar Younis & Peter Ludwig, Applied Intuition

Latent Space: The AI Engineer Podcast

1:12:21Apr 27, 2026
AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026) artwork

AIE Europe Debrief + Agent Labs Thesis: Unsupervised Learning x Latent Space Crossover Special (2026)

Latent Space: The AI Engineer Podcast

54:52Apr 23, 2026
Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO artwork

Shopify’s AI Phase Transition: 2026 Usage Explosion, Unlimited Opus-4.6 Token Budget, Tangle, Tangent, SimGym — with Mikhail Parakhin, Shopify CTO

Latent Space: The AI Engineer Podcast

1:12:25Apr 22, 2026
🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik artwork

🔬 Training Transformers to solve 95% failure rate of Cancer Trials — Ron Alfa & Daniel Bear, Noetik

Latent Space: The AI Engineer Podcast

1:25:21Apr 20, 2026
Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion artwork

Notion’s Token Town: 5 Rebuilds, 100+ Tools, MCP vs CLIs and the Software Factory Future — Simon Last & Sarah Sachs of Notion

Latent Space: The AI Engineer Podcast

1:17:17Apr 15, 2026
Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony artwork

Extreme Harness Engineering for Token Billionaires: 1M LOC, 1B toks/day, 0% human code, 0% human review — Ryan Lopopolo, OpenAI Frontier & Symphony

Latent Space: The AI Engineer Podcast

1:12:43Apr 7, 2026
Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different" artwork

Marc Andreessen introspects on The Death of the Browser, Pi + OpenClaw, and Why "This Time Is Different"

Latent Space: The AI Engineer Podcast

1:16:20Apr 3, 2026
Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun artwork

Moonlake: Causal World Models should be Multimodal, Interactive, and Efficient — with Chris Manning and Fan-yun Sun

Latent Space: The AI Engineer Podcast

1:06:47Apr 2, 2026
Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample artwork

Mistral: Voxtral TTS, Forge, Leanstral, & what's next for Mistral 4 — w/ Pavan Kumar Reddy & Guillaume Lample

Latent Space: The AI Engineer Podcast

48:48Mar 30, 2026
🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik artwork

🔬Why There Is No "AlphaFold for Materials" — AI for Materials Discovery with Heather Kulik

Latent Space: The AI Engineer Podcast

35:14Mar 24, 2026
Dreamer: the Personal Agent OS — David Singleton artwork

Dreamer: the Personal Agent OS — David Singleton

Latent Space: The AI Engineer Podcast

1:03:35Mar 20, 2026
Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop artwork

Why Anthropic Thinks AI Should Have Its Own Computer — Felix Rieseberg of Claude Cowork & Claude Code Desktop

Latent Space: The AI Engineer Podcast

1:26:59Mar 17, 2026