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RFK Jr. Wants To Take Your SSRIs Away. So What Are Democrats Doing About It?
Depresh Mode with John Moe
50:15Jun 15, 2026
Robyn Hitchcock is Fundamentally Delusional, Welcomes Birds
Depresh Mode with John Moe
1:04:46Jun 8, 2026
Blake Mycoskie Helped the World, Got Rich, Retired to a Life of Ease, Then Fell Apart
Depresh Mode with John Moe
58:16Jun 1, 2026
An Episode About the Grind, Singer Zayna Youssef of Sweet Pill, and YOU
Depresh Mode with John Moe
53:51May 25, 2026
Terrifying Times for Immigrants in America and Cristina Jimínez is Incredibly Hopeful
Depresh Mode with John Moe
44:53May 18, 2026
Claude Steele on Churn, the Awkward Social Distress That Divides Us All
Depresh Mode with John Moe
55:46May 11, 2026
Connecting Childhood Events To Your Stress Issues Today with Benjamin Wagner
Depresh Mode with John Moe
52:10May 4, 2026
Sampler Episode Depresh Meals
Depresh Mode with John Moe
7:13May 1, 2026
Bonus mini-sode: Checking In with Bill Corbett
Depresh Mode with John Moe
18:29Apr 30, 2026
Bonus Mini-Sode: A Dramatic Reading by Helen Hong and Interview with Playwright Sunny Kase
Depresh Mode with John Moe
18:34Apr 29, 2026
Casters on Casters: John Moe and Brenda Snell
Depresh Mode with John Moe
17:14Apr 28, 2026
Andy Richter on Divorce, Dating, Depression, and Dancing with the Stars
Depresh Mode with John Moe
1:07:18Apr 27, 2026
Bonus mini-sode: Checking In with Felicia Day
Depresh Mode with John Moe
25:45Apr 23, 2026
BONUS CONTENT PREVIEW: All-Star Sad Songs That Make You Feel Better with Neko Case, Gavin Rossdale, and more
Depresh Mode with John Moe
8:12Apr 21, 2026
Jimmy Pardo on Being Funny, Depression, Anxiety, Trauma, Alcoholism, Contentment, and Being Funny Some More
Depresh Mode with John Moe
1:14:23Apr 20, 2026
Joshua Roman on Long Covid, Cello, Charging Hard, and Brick Walls
Depresh Mode with John Moe
1:01:18Apr 13, 2026
Featuring Proxy with Yowei Shaw: Is it time to break up the band?
Depresh Mode with John Moe
51:44Apr 6, 2026
Annabelle Gurwitch: Author, Actor, Unexpectedly Still Alive
Depresh Mode with John Moe
1:01:29Mar 30, 2026
Taking Small Steps That Form Great Strides with Eric Zimmer
Depresh Mode with John Moe
44:44Mar 23, 2026
Bonus Episode from In This Family: Ka Vang on War in Southeast Asia, ICE in Minnesota, and Mental Health Echoes
Depresh Mode with John Moe
59:04Mar 18, 2026
Bubbles of Love: Your Burnout Treatment, with Emily Nagoski
Depresh Mode with John Moe
56:39Mar 16, 2026
Group Therapy Royalty and First-Time Movie Star Elliot Zeisel From GROUP
Depresh Mode with John Moe
43:18Mar 9, 2026
Jonathan Edward Durham Was In Horrible Mental Shape But Didn’t Realize It
Depresh Mode with John Moe
51:13Mar 2, 2026
Huge Scientific Breakthroughs Are Changing How You’ll Think About Eating Disorders
Depresh Mode with John Moe
1:00:39Feb 23, 2026
Are Dating Apps a Mental Health Grenade? And, How Are Kids Doing in ICE-Era Minnesota?
Depresh Mode with John Moe
51:27Feb 16, 2026
Niko Stratis on Dad Rock, Glasswork, Depression, Addiction, and Becoming Herself
Depresh Mode with John Moe
58:03Feb 9, 2026
SPECIAL EPISODE: Mental Health and ICE in Minnesota
Depresh Mode with John Moe
23:08Feb 6, 2026
Amanda Knox on Facing Her Prosecutor, Her Past, Her Trauma, and Her Future
Depresh Mode with John Moe
54:53Feb 2, 2026
Intentionally Blunt and Very Useful Talk About Suicide with Clancy Martin
Depresh Mode with John Moe
1:03:23Jan 26, 2026
Stephanie Foo on Complex PTSD, Finding Recovery, and This American Life
Depresh Mode with John Moe
52:24Jan 19, 2026
A.J. Daulerio on Bipolar, Substances, Depression, Suicide, and the Psychic Weight of Hulk Hogan
Depresh Mode with John Moe
58:04Jan 12, 2026
Two Truths To Make 2026 a Better Mental Health Year
Depresh Mode with John Moe
41:58Jan 5, 2026
Mike Doughty Was Recently Hospitalized for Depression Twice. It Helped.
Depresh Mode with John Moe
45:57Dec 29, 2025
Tom Johnson Advised LBJ, Ran CNN, and Drove Himself to Severe Depression
Depresh Mode with John Moe
40:53Dec 22, 2025
Anger: Let’s Talk About It, Learn About It, Not Fear It, Use It For Good
Depresh Mode with John Moe
46:40Dec 15, 2025
Unemployment Hurts Mental Health, Horror Movies Might Help It. Really!
Depresh Mode with John Moe
35:43Dec 8, 2025
Maureen Johnson Became Friends with Her Anxiety Monster
Depresh Mode with John Moe
45:26Dec 1, 2025
A Holiday Family Survival Mini-sode
Depresh Mode with John Moe
18:21Nov 26, 2025
Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
Depresh Mode with John Moe
1:01:49Nov 24, 2025
Is Your Mental Health Diagnosis an Identity or Something More Meaningless?
Depresh Mode with John Moe
59:40Nov 17, 2025
The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
Depresh Mode with John Moe
37:33Nov 10, 2025
Seasonal Affective Disorder and Why It Sucks So Bad
Depresh Mode with John Moe
41:09Nov 3, 2025
Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
Depresh Mode with John Moe
48:00Oct 27, 2025
Is the U.S. Government Going To Take Away Your Antidepressants?
Depresh Mode with John Moe
42:04Oct 20, 2025
P.E. Moskowitz on Whether Your Mind is Broken or the World Is
Depresh Mode with John Moe
56:22Oct 13, 2025
Kendall Toole Gets Knocked Down, Never Knocked Out
Depresh Mode with John Moe
42:46Oct 6, 2025
Bruce Springsteen as Over-The-Counter Depression Treatment
Depresh Mode with John Moe
47:10Sep 29, 2025
Emma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.
Depresh Mode with John Moe
47:06Sep 22, 2025
Sycophantic Chatbots and Alarming Cases of “AI Psychosis”
Depresh Mode with John Moe
50:41Sep 15, 2025
Alex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper